Botulinum Toxin

Botulinum toxin a muscle-relaxing medication. It’s made from bacteria called clostridium botulinum. It plays a significant role in the management of a variety of medical conditions. Also it treats some chronic conditions that respond only partially to medical treatment. A list of possible new indications is rapidly expanding. It is now used in almost every sub-specialty of medicine. Cosmetological applications include.

  • The correction of lines and wrinkles.
  • Reduce Gummy Smiles and Balance Uneven Lips.
  • Brow lift.

 Dermatological applications include.

  •  Hyperhidrosis.
  • Hypertrophic Scar Treatment.

Injections with botulinum toxins are well tolerated, with a few side effects. The weakness induced by injection lasts about three months.

What is botulinum toxin

It is a neurotoxic protein produced by the bacterium Clostridium botulinum, with its related species. It prevents the release of the neurotransmitter acetylcholine from axon endings, at the neuromuscular junction. This action causes flaccid paralysis.

Types of botulinum toxin

Seven serologically distinct types of botulinum toxins exist: A, B, C1, D, E, F, and G. Commercial forms are marketed under the brand names. Which include Botox, Dysport, Azzalure, Xeomin, and Bocouture. They differ in molecular sizes, degrees of activation, and mechanisms of action. Type A is a popular injectable which includes Botox. It temporarily reduces or eliminates facial fine lines and wrinkles.

Uses for botulinum toxin

Medical uses include.

Migraine headache.

Migraine sufferers are among those most likely to benefit from botulinum injections. The FDA approved botulinum for the treatment of chronic migraines on October 15, 2010.  After receiving and reviewing two large multi-center trials. Generally, migraines last anywhere from four hours to three days. At the same time chronic migraines last 15 or more days a month. However botulinum injections prevent pain signals from reaching nerve endings.


Pain from any neuralgia-type condition finds relief with botulinum toxin injections. Neuralgia is an intense, shooting pain along a nerve pathway. It comes as a result of nerve damage or dysfunction. This could happen off and on or constant. It can follow a complication of shingles known as postherpetic neuralgia, as well as trigeminal neuralgia. On the other hand occipital neuralgia with symptoms similar to migraine headaches is also treated with injections.

Spasticity (involuntary muscle tightening).

Injections can reduce spasticity or involuntary muscle tightening. Which comes as a result of traumatic brain injury, cerebral palsy, multiple sclerosis, stroke, or spinal cord injury.

Excessive sweating.

Excessive sweating in feet, underarms, hands, legs and armpits is treated with botulinum injections. The toxin blocks the chemical signals from the nerves that stimulate the sweat glands in the target area.

Overactive bladder.

People who struggle with overactive bladder can find relief with injections into the wall of the bladder. This reduces the sudden intense urge to urinate during the day. Also it allows them to sleep through the night.

 Eye twitching.

 An injection of toxin can stop an uncontrollable eyelid twitch for several months.

Teeth grinding.

Excessive grinding of the teeth causes tooth damage and pain. Injections of botulinum relieve the pressure on the teeth. It also reduces the risk of damage by weakening the muscle that causes grinding.

How long do botulinum toxin last

The toxin requires 24-72 hours to take effect. Some individuals may require as many as five days for the full effect in very rare circumstances. Peaking at about 10 days. The effect of botulinum toxin lasts nearly 8-12 weeks

How does botulinum work

When injected, It blocks certain nerve signals that make muscles contract. Thus muscles relax, reducing unwanted wrinkles. This effect lasts about 3 months. Afterward, the muscles move again and wrinkles come back. When you have botulinum toxin injected. Your doctor may first rub an anesthetic cream on the area to numb it. Then he or she will inject the medicine into specific facial muscles. This only takes a few minutes. And can be done right in the doctor’s office. You will be able to continue your daily activities right afterward. About 3 days after the injection, you should notice some muscles starting to relax. After 1 week, you likely will see fewer facial wrinkles and lines. This effect wears off in about 3–6 months.

How botulinum toxin is given

Botulinum toxin is injected into the target muscles or glands using a 30-gauge 1-inch needle. Doses are according to the mode of use. The dose depends on the mass of muscle. The larger the muscle mass the higher the dose. However, lower doses in females and for patients with preexisting weakness.

Precautions after botulinum toxin 

One should go home immediately and rest after a botulinum injection. Do nothing strenuous for one or two days. Refrain from laser treatments, facials and facial massage for one to two weeks. This is to minimize toxins dislodging and traveling to the surrounding muscles.

Who can get botulinum toxin injections?

You need to be healthy and at least 18 years old before you can get botulinum toxin injections.

Some people should not get botulinum toxin. They include those who:

  • Have a neuromuscular disease
  • Are pregnant or nursing
  • Weakness in certain facial muscles
  • Have ptosis (drooping eyelids) deep facial scars, very thick facial skin, or uneven facial features (when features are not the same on both sides of the face)
  • Skin problems near the injection area

If you are planning to get botulinum toxin injections. Tell your doctor about your medical history and all the prescription medicines, vitamins, and herbal supplements you take.

While botulinum toxin injections may help, they sometimes cause side effects or other health problems. Common side effects include.

  • Headache
  • Eye redness, tearing, or irritation
  • Redness or bruising in the injection area. This is more likely to happen if you take aspirin or blood-thinning medicine. Ask your doctor if you should stop taking those medicines a few days before getting a botulinum toxin injection.

A less common but more serious side effect is ptosis (drooping eyelids). This can make it hard to see. Ptosis should go away when the botulinum toxin wears off in a couple of months.

To help reduce the possibility of side effects, your doctor may recommend using eye drops or ointment after a botulinum toxin injection. You may also be asked to sit upright (not lie down) and avoid pressing on the target area for about 4 hours after the injection. Also, your doctor may recommend you not exercise for 24 hours after treatment.

Botulinum toxin cost

The cost can vary widely depending on factors. Such as the type of botulinum toxin.

Botulinum toxin for sale 

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Important Information

The botulinum toxin can spread to other body areas beyond where it was injected. This can cause serious life-threatening side effects. Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe eye irritation, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing.

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